Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 8e8l
Q-score: 0.477
Charnesky AJ, Faust JE, Lee H, Puligedda RD, Goetschius DJ, DiNunno NM, Thapa V, Bator CM, Cho SHJ, Wahid R, Mahmood K, Dessain S, Chumakov KM, Rosenfeld A, Hafenstein SL
Nat Commun (2023) 14 pp. 6335-6335 [ Pubmed: 37816742 DOI: doi:10.1038/s41467-023-41052-9 ]
- Capsid protein vp1 (31 kDa, Protein from Human poliovirus 1 Mahoney)
- 9h2 fab light chain (11 kDa, Protein from Homo sapiens)
- Capsid protein vp4 (7 kDa, Protein from Human poliovirus 1 Mahoney)
- Human poliovirus 1 mahoney (Virus from Human poliovirus 1 Mahoney)
- Capsid protein vp2 (29 kDa, Protein from Human poliovirus 1 Mahoney)
- 9h2 fab heavy chain (14 kDa, Protein from Homo sapiens)
- Capsid protein vp3 (26 kDa, Protein from Human poliovirus 1 Mahoney)
9H2 Fab-Sabin poliovirus 3 complex
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 8e8r
Q-score: 0.595
Charnesky AJ, Faust JE, Lee H, Puligedda RD, Goetschius DJ, DiNunno NM, Thapa V, Bator CM, Cho SHJ, Wahid R, Mahmood K, Dessain S, Chumakov KM, Rosenfeld A, Hafenstein SL
Nat Commun (2023) 14 pp. 6335-6335 [ Pubmed: 37816742 DOI: doi:10.1038/s41467-023-41052-9 ]
- Capsid protein vp2 (29 kDa, Protein from Human poliovirus 3 strain Sabin)
- Human poliovirus 3 strain sabin (Virus from Human poliovirus 3 strain Sabin)
- Palmitic acid (256 Da, Ligand)
- 9h2 fab light chain (11 kDa, Protein from Homo sapiens)
- Capsid protein vp3 (25 kDa, Protein from Human poliovirus 3 strain Sabin)
- 9h2 fab heavy chain (14 kDa, Protein from Homo sapiens)
- Capsid protein vp4 (7 kDa, Protein from Human poliovirus 3 strain Sabin)
- Capsid protein vp1 (31 kDa, Protein from Human poliovirus 3 strain Sabin)
Resolution: 2.73 Å
EM Method: Single-particle
Fitted PDBs: 8e8s
Q-score: 0.573
Charnesky AJ, Faust JE, Lee H, Puligedda RD, Goetschius DJ, DiNunno NM, Thapa V, Bator CM, Cho SHJ, Wahid R, Mahmood K, Dessain S, Chumakov KM, Rosenfeld A, Hafenstein SL
Nat Commun (2023) 14 pp. 6335-6335 [ Pubmed: 37816742 DOI: doi:10.1038/s41467-023-41052-9 ]
- Capsid protein vp1 (30 kDa, Protein from Poliovirus 2)
- Capsid protein vp3 (26 kDa, Protein from Poliovirus 2)
- Palmitic acid (256 Da, Ligand)
- Capsid protein vp2 (29 kDa, Protein from Poliovirus 2)
- 9h2 fab light chain (11 kDa, Protein from Homo sapiens)
- Capsid protein vp4 (7 kDa, Protein from Poliovirus 2)
- 9h2 fab heavy chain (14 kDa, Protein from Homo sapiens)
- Human poliovirus 2 (Virus from Human poliovirus 2)
9H2 Fab-Sabin poliovirus 3 complex
Resolution: 2.91 Å
EM Method: Single-particle
Fitted PDBs: 8e8x
Q-score: 0.521
Charnesky AJ, Faust JE, Lee H, Puligedda RD, Goetschius DJ, DiNunno NM, Thapa V, Bator CM, Cho SHJ, Wahid R, Mahmood K, Dessain S, Chumakov KM, Rosenfeld A, Hafenstein SL
Nat Commun (2023) 14 pp. 6335-6335 [ Pubmed: 37816742 DOI: doi:10.1038/s41467-023-41052-9 ]
- Capsid protein vp2 (29 kDa, Protein from Human poliovirus 3 strain Sabin)
- Human poliovirus 3 strain sabin (Virus from Human poliovirus 3 strain Sabin)
- Palmitic acid (256 Da, Ligand)
- 9h2 fab light chain (11 kDa, Protein from Homo sapiens)
- Capsid protein vp3 (25 kDa, Protein from Human poliovirus 3 strain Sabin)
- 9h2 fab heavy chain (14 kDa, Protein from Homo sapiens)
- Capsid protein vp4 (7 kDa, Protein from Human poliovirus 3 strain Sabin)
- Capsid protein vp1 (31 kDa, Protein from Human poliovirus 3 strain Sabin)
9H2 Fab-Sabin poliovirus 2 complex
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8e8y
Q-score: 0.533
Charnesky AJ, Faust JE, Lee H, Puligedda RD, Goetschius DJ, DiNunno NM, Thapa V, Bator CM, Cho SHJ, Wahid R, Mahmood K, Dessain S, Chumakov KM, Rosenfeld A, Hafenstein SL
Nat Commun (2023) 14 pp. 6335-6335 [ Pubmed: 37816742 DOI: doi:10.1038/s41467-023-41052-9 ]
- Capsid protein vp4 (7 kDa, Protein from Human poliovirus 2 strain Sabin)
- Capsid protein vp1 (30 kDa, Protein from Human poliovirus 2 strain Sabin)
- Palmitic acid (256 Da, Ligand)
- 9h2 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Human poliovirus 2 strain sabin (Virus from Human poliovirus 2 strain Sabin)
- 9h2 fab light chain (11 kDa, Protein from Homo sapiens)
- Capsid protein vp3 (26 kDa, Protein from Human poliovirus 2 strain Sabin)
- Capsid protein vp2 (29 kDa, Protein from Human poliovirus 2 strain Sabin)
9H2 Fab-Sabin poliovirus 1 complex
Resolution: 3.15 Å
EM Method: Single-particle
Fitted PDBs: 8e8z
Q-score: 0.496
Charnesky AJ, Faust JE, Lee H, Puligedda RD, Goetschius DJ, DiNunno NM, Thapa V, Bator CM, Cho SHJ, Wahid R, Mahmood K, Dessain S, Chumakov KM, Rosenfeld A, Hafenstein SL
Nat Commun (2023) 14 pp. 6335-6335 [ Pubmed: 37816742 DOI: doi:10.1038/s41467-023-41052-9 ]
- Capsid protein vp1 (31 kDa, Protein from Human poliovirus 1 strain Sabin)
- Capsid protein vp2 (29 kDa, Protein from Human poliovirus 1 strain Sabin)
- Human poliovirus 1 strain sabin (Virus from Human poliovirus 1 strain Sabin)
- Capsid protein vp3 (26 kDa, Protein from Human poliovirus 1 strain Sabin)
- Capsid protein vp4 (7 kDa, Protein from Human poliovirus 1 strain Sabin)
- 9h2 fab light chain (11 kDa, Protein from Homo sapiens)
- 9h2 fab heavy chain (13 kDa, Protein from Homo sapiens)
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8ayx
Q-score: 0.649
Bahar MW, Nasta V, Fox H, Sherry L, Grehan K, Porta C, Macadam AJ, Stonehouse NJ, Rowlands DJ, Fry EE, Stuart DI
Commun Biol (2022) 5 pp. 1293-1293 [ DOI: doi:10.1038/s42003-022-04252-5 Pubmed: 36434067 ]
- Capsid protein, vp3 (26 kDa, Protein from Human poliovirus 3)
- Human poliovirus 3 (5 MDa, Virus from Human poliovirus 3)
- Capsid protein, vp1 (33 kDa, Protein from Human poliovirus 3)
- 1-[(3s)-5-[4-[(e)-ethoxyiminomethyl]phenoxy]-3-methyl-pentyl]-3-pyridin-4-yl-imidazolidin-2-one (410 Da, Ligand)
- Capsid protein, vp0 (37 kDa, Protein from Human poliovirus 3)
- Glutathione (307 Da, Ligand)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8ayy
Q-score: 0.647
Bahar MW, Nasta V, Fox H, Sherry L, Grehan K, Porta C, Macadam AJ, Stonehouse NJ, Rowlands DJ, Fry EE, Stuart DI
Commun Biol (2022) 5 pp. 1293-1293 [ DOI: doi:10.1038/s42003-022-04252-5 Pubmed: 36434067 ]
- Capsid protein, vp3 (26 kDa, Protein from Human poliovirus 3)
- Human poliovirus 3 (5 MDa, Virus from Human poliovirus 3)
- Capsid protein, vp1 (33 kDa, Protein from Human poliovirus 3)
- 3-{3,5-dimethyl-4-[3-(3-methyl-isoxazol-5-yl)-propoxy]-phenyl}-5-trifluoromethyl-[1,2,4]oxadiazole (381 Da, Ligand)
- Capsid protein, vp0 (37 kDa, Protein from Human poliovirus 3)
- Glutathione (307 Da, Ligand)
Poliovirus type 2 (strain MEF-1) virus-like particle in complex with capsid binder compound 17
Resolution: 1.88 Å
EM Method: Single-particle
Fitted PDBs: 8ayz
Q-score: 0.769
Bahar MW, Nasta V, Fox H, Sherry L, Grehan K, Porta C, Macadam AJ, Stonehouse NJ, Rowlands DJ, Fry EE, Stuart DI
Commun Biol (2022) 5 pp. 1293-1293 [ DOI: doi:10.1038/s42003-022-04252-5 Pubmed: 36434067 ]
- Capsid protein, vp0 (37 kDa, Protein from Human poliovirus 2)
- Water (18 Da, Ligand)
- Capsid protein, vp1 (33 kDa, Protein from Human poliovirus 2)
- 4-[[4-[1,3-bis(oxidanylidene)isoindol-2-yl]phenyl]sulfonylamino]benzoic acid (422 Da, Ligand)
- Sphingosine (299 Da, Ligand)
- Human poliovirus 2 (5 MDa, Virus from Human poliovirus 2)
- Capsid protein, vp3 (26 kDa, Protein from Human poliovirus 2)
In situ subtomogram average of autophagosome-associated protein filament
Dahmane S, Kerviel A, Morado DR, Shankar K, Ahlman B, Lazarou M, Altan-Bonnet N, Carlson LA
Nat Commun (2022) 13 pp. 5986-5986 [ Pubmed: 36216808 DOI: doi:10.1038/s41467-022-33483-7 ]